MAPK6 anticorps

N° du produit ABIN317885

Détail du produit anti-MAPK6 anticorps

Antigène: MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK6 est non-conjugé

Application: Western Blotting (WB)

Specificité: ERK3 antibody detects endogenous levels of ERK3 protein.(region surrounding Lys185)

Purification: Affinity chromatography

Information d'application

Indications d'application: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MAPK6

Antigène: MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

Autre désignation: MAPK6 / ERK3 (MAPK6 Produits)

Synonymes: anticorps ERK3, anticorps HsT17250, anticorps PRKM6, anticorps p97MAPK, anticorps 2610021I23Rik, anticorps D130053K17Rik, anticorps Erk3, anticorps Mapk4, anticorps Mapk63, anticorps Prkm4, anticorps Prkm6, anticorps ATMAPK6, anticorps ATMPK6, anticorps F18O19.10, anticorps MAP KINASE 6, anticorps MAP kinase 6, anticorps MAPK6, anticorps SUSERK3, anticorps erk3, anticorps p97mapk, anticorps si:ch211-235f12.1, anticorps mitogen-activated protein kinase 6, anticorps MAP kinase 6, anticorps MAPK6, anticorps Mapk6, anticorps MPK6, anticorps mapk6

Sujet: Mitogen-activated protein kinase (MAPK) signaling pathways involve closely related MAP kinases, including extracellular-signal-related kinase 3 (ERK 3, also designated PRKM6 and p97MAPK). Serum, growth factors and phorbol esters can initiate ERK 3 signaling pathways. Despite lacking a definitive nuclear localization sequence, ERK 3 constitutively localizes to the nucleus upon activation. p38 pathway activation-dependent upregulation of ERK 3 is independent of the status of p53, Bcl2 and caspase 3 during cell stress and damage induced by proteasome inhibition, suggesting ERK 3 in part mediates intracellular defense or cell rescue. The human ERK3 gene maps to chromosome 15q21 and encodes a 721 amino acid protein.Synonyms: Extracellular signal-regulated kinase 3, MAP kinase isoform p97, Mitogen-activated protein kinase 6, Serine/threonine-protein kinase, p97-MAPK

Poids moléculaire: approx. 83 kDa

ID gène: 5597

NCBI Accession: NP_002739

UniProt: Q16659

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C