NOXA anticorps (N-Term)

N° du produit ABIN318707

L’anticorps anti-NOXA Polyclonal Lapin est utilisé pour la détection de NOXA dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et IHC (p).

Aperçu rapide pour NOXA anticorps (N-Term) (ABIN318707)

Antigène: NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOXA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-NOXA anticorps

Épitope: N-Term

Specificité: This antibody recognises murine Noxa.

Purification: Purified

Immunogène: Synthetic peptide corresponding to N-terminus of mouse NOXA.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 0.5 - 1.0g/mL, detects a band of approximately 11 kDa in human stomach celllysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5mg/mL

Buffer: Phosphate buffered saline containing 0.02 % Sodium Azide (NaN3)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur NOXA

Antigène: NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))

Autre désignation: NOXA

Sujet: Noxa is an 11 kDa member of the BH3-only proapoptotic protein family. Noxa is localised to the mitochondria and is a transcriptional target of p73, p53 and BH3-only proteins. It is thought to induce apoptosis when activated, lowering the activity of anti-apoptotic Bcl-2-like proteins. It can be upregulated by mitogenic activation, independently of p53. In humans, along with Mcl-1 it is thought to form a selective pathway that restrains lymphocyte proliferation.Synonyms: PMA-induced protein 1, PMAIP1, Phorbol-12-myristate-13-acetate-induced protein 1

ID gène: 5366

NCBI Accession: NP_066950

UniProt: Q13794

Pathways: Signalisation p53, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus