IL23A anticorps (N-Term)

N° du produit ABIN318745

Détail du produit anti-IL23A anticorps

Antigène: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL23A est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects an epitope within the N-terminal (NT) domain of human interleukin-23 (IL-23).

Purification: Purified

Immunogène: A 16 amino acid peptide from near the amino terminus of human IL-23.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1 - 2g/mL, detects a band of approximately 24 kDa in mouse pancreas tissuelysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.02 % Sodium Azide (NaN3)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur IL23A

Antigène: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Autre désignation: Interleukin-23 alpha / IL23A (IL23A Produits)

Synonymes: anticorps IL-23, anticorps IL-23A, anticorps IL23P19, anticorps P19, anticorps SGRF, anticorps FIL1, anticorps FIL1(ZETA), anticorps FIL1Z, anticorps IL-1F7, anticorps IL-1H, anticorps IL-1H4, anticorps IL-1RP1, anticorps IL-37, anticorps IL1F7, anticorps IL1H4, anticorps IL1RP1, anticorps p19, anticorps il23p19, anticorps IL23, anticorps interleukin 23 subunit alpha, anticorps interleukin 37, anticorps interleukin 23, alpha subunit p19, anticorps IL23A, anticorps IL37, anticorps Il23a

Sujet: IL23 is a 21kD heterodimeric cytokine structurally related to IL-12. IL-23 is composed of a p19 subunit encoded by the IL23A gene, and a p40 subunit of interleukin-12 (IL12B). IL-23 is expressed mainly by activated macrophages and dendritic cells, and plays an important role in bridging innate and adaptive responses. IL-23 activates a subset of T cells called Th17 cells, which are characterised by the production of interleukin-17. The IL-23/IL-17 pathway is essential for the induction and maintenance of brain and joint inflammatory autoimmune diseases, including Guillain Barre Syndrome, Multiple sclerosis and rheumatoid arthritis.Synonyms: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF

ID gène: 51561

NCBI Accession: NP_057668

UniProt: Q9NPF7

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation