USP11 anticorps

N° du produit ABIN334288

Détail du produit anti-USP11 anticorps

Antigène: USP11 (Ubiquitin Specific Peptidase 11 (USP11))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP11 est non-conjugé

Application: Immunohistochemistry (IHC)

Immunogène: Partial peptide of Mouse Usp11

Information d'application

Indications d'application: IHC: 5.0-10 ug/mL (Paraffin embedded Sections)

Restrictions: For Research Use only

Stockage

Concentration: 0.25 mg/ml

Buffer: PBS [containing 2 % Block Ace as a stabilizer, 0.1 %Proclin as a bacteriostat]

Agent conservateur: ProClin

Stock: -20 °C

Détails sur USP11

Antigène: USP11 (Ubiquitin Specific Peptidase 11 (USP11))

Autre désignation: Usp11 (USP11 Produits)

Synonymes: anticorps USP11, anticorps DKFZp459L098, anticorps UHX1, anticorps 6230415D12Rik, anticorps mKIAA4085, anticorps Uhx1, anticorps ubiquitin specific peptidase 11, anticorps universal stress protein, anticorps USP11, anticorps RR_RS19935, anticorps Usp11

Sujet: Usp11 (ubiquitin specific peptidase 11) possesses Cys box, His box, Asp and KRF domains, which are highly conserved in many ubiquitin-specific proteases. Usp11 is a ubiquitous protein in various tissues and is primarily localized in the nucleus of non-dividing cells. Usp11 binds specifically to RanBPM which is a RanGTP-binding protein required for correct nucleation of microtubles and inhibits its ubiquitination and degradation. It has been also shown that Usp11 is involved in regulation of the TNFalpha-induced IKKalpha --> p53 signaling pathway and that Usp11 functions in stabilizing HPV-16E7 by reducing ubiquitination and attenuating E7 degradation. Alternate Names: MGC6649, KIAA4085, mKIAA4085, 6230415D12Rik, Usp11 ubiquitin specific peptidase 11.

ID gène: 236733