NOTCH3 anticorps (AA 2306-2318)

N° du produit ABIN337107

Cet anticorps anti-NOTCH3 Polyclonal Chèvre (ABIN337107) détecte spécifiquement NOTCH3 dans ELISA, IHC et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Singe et Roussette (Chauve-souris).

Aperçu rapide pour NOTCH3 anticorps (AA 2306-2318) (ABIN337107)

Antigène: NOTCH3 (Notch 3 (NOTCH3))

Reactivité: Humain, Souris, Rat, Singe, Roussette (Chauve-souris)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp NOTCH3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-NOTCH3 anticorps

Épitope: AA 2306-2318

Specificité: Human NOTCH3.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Rat, Panda, Bat (100%) Hamster, Bovine (92%) Elephant (85%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide C-QLGPQPEVTPKRQ from the C-terminus of human NOTCH3 (NP_000426.2). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Rat, Panda, Bat (100%), Hamster, Bovine (92%), Elephant (85%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA (1:16000)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur NOTCH3

Antigène: NOTCH3 (Notch 3 (NOTCH3))

Autre désignation: NOTCH3

Sujet: Name/Gene ID: NOTCH3
Family: Fibronectin

Synonyms: NOTCH3, CASIL, CADASIL, Notch 3, Notch (Drosophila) homolog 3, Notch homolog 3, Notch homolog 3 (Drosophila)

ID gène: 4854

NCBI Accession: NP_000426

UniProt: Q9UM47

Pathways: Signalisation Notch