CD14 anticorps (AA 147-152)
-
- Antigène Voir toutes CD14 Anticorps
- CD14
-
Épitope
- AA 147-152
-
Reactivité
- Humain
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp CD14 est non-conjugé
-
Application
- Flow Cytometry (FACS), Immunofluorescence (IF), Agonist (Agon)
- Specificité
- Soluble and membrane bound human CD14. The antibody does'nt significant block LPS binding to membrane bound CD14.
- Purification
- Protein G affinity column
- Immunogène
- human Monocytes
- Clone
- BiG2
- Isotype
- IgG1
- Top Product
- Discover our top product CD14 Anticorps primaire
-
-
- Indications d'application
- no significant inhibition of LPS binding to CD14
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Reconstitute with bidistilled water
- Concentration
- 1 mg/mL
- Buffer
- PBS, pH 7.7
- Agent conservateur
- Without preservative
- Stock
- -20 °C,-80 °C
-
-
Differential impact of substitution of amino acids 9-13 and 91-101 of human CD14 on soluble CD14-dependent activation of cells by lipopolysaccharide." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 11, pp. 6035-44, (1999) (PubMed).
: "Binding of bacterial peptidoglycan to CD14." dans: The Journal of biological chemistry, Vol. 273, Issue 15, pp. 8680-90, (1998) (PubMed).
: "Low endotoxic potential of Legionella pneumophila lipopolysaccharide due to failure of interaction with the monocyte lipopolysaccharide receptor CD14." dans: Infection and immunity, Vol. 66, Issue 9, pp. 4151-7, (1998) (PubMed).
: "
-
Differential impact of substitution of amino acids 9-13 and 91-101 of human CD14 on soluble CD14-dependent activation of cells by lipopolysaccharide." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 11, pp. 6035-44, (1999) (PubMed).
-
- Antigène
- CD14
- Autre désignation
- CD14 (CD14 Produits)
- Synonymes
- anticorps CD14 molecule, anticorps CD14 antigen, anticorps CD14, anticorps Cd14
- Sujet
- Background: biG 2 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.
- Poids moléculaire
- ~50kDa
- ID gène
- 929
- NCBI Accession
- NP_000582
- UniProt
- P08571
- Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
-