CD14 anticorps
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- Antigène Voir toutes CD14 Anticorps
- CD14
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Reactivité
- Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD14 est non-conjugé
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Application
- ELISA
- Specificité
- Recombinant mouse CD14. The antibody don't blocks LPS binding to membrane bound CD14.
- Purification
- Protein G affinity column
- Immunogène
- recombinant mouse CD14
- Clone
- BiG57
- Isotype
- IgG1
- Top Product
- Discover our top product CD14 Anticorps primaire
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- Indications d'application
- ELISA , immunostaining of mouse macrophages after stimulation 6h with LPS, Western blot with recombinant mouse CD14. Binding titre at mouse CD14 transfected CHO-cells: more than 100.000 (ELISA, Flow cytometry), no binding at LPS-binding site, endotoxin content less than 0.1ng/ml
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with bidistilled water
- Concentration
- 1 mg/mL
- Buffer
- PBS, pH 7.15
- Agent conservateur
- Without preservative
- Stock
- -20 °C,-80 °C
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- Antigène
- CD14
- Autre désignation
- CD14 (CD14 Produits)
- Synonymes
- anticorps CD14 molecule, anticorps CD14 antigen, anticorps CD14, anticorps Cd14
- Sujet
- Background: biG 57 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.
- Poids moléculaire
- ~50kDa
- ID gène
- 12475
- NCBI Accession
- NP_033971
- UniProt
- P10810
- Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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