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CD14 anticorps

CD14 Reactivité: Souris ELISA Hôte: Souris Monoclonal biG53 unconjugated
N° du produit ABIN343180
  • Antigène Voir toutes CD14 Anticorps
    CD14
    Reactivité
    • 269
    • 55
    • 32
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    • 14
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    • 2
    • 2
    • 1
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    Souris
    Hôte
    • 225
    • 64
    • 25
    • 3
    • 1
    Souris
    Clonalité
    • 254
    • 64
    Monoclonal
    Conjugué
    • 129
    • 30
    • 24
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    • 15
    • 8
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    • 5
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    • 2
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    • 2
    • 1
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    Cet anticorp CD14 est non-conjugé
    Application
    • 224
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    • 50
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    ELISA
    Specificité
    Membrane bound and soluble mouse CD14. The antibody blocks LPS binding to membrane bound CD14.
    Purification
    Protein A affinity column
    Immunogène
    Monocytes of mouse
    Clone
    BiG53
    Isotype
    IgG1
    Top Product
    Discover our top product CD14 Anticorps primaire
  • Indications d'application
    Suitable for immunostaining of CD14 positive cells and inhibition studies Binds at LPS activated mouse monocytes as well as mouse CD14 transfected cells or recombinant mouse CD14 ELISA. Inhibition of LPS binding to CD14 (Binding at LPS binding site). Up to 1 ug/ml biG53 inhibit binding of FITC-LPS (0.5ug/ml) to 6 x 105 CD14+CHO transfectants (FACS), Binding titre at mouse CD14 transfected CHO-cells: more than 20.000 (ELISA, Flow cytometry)
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with bidistilled water
    Concentration
    1 mg/mL
    Buffer
    PBS, pH 7.16
    Agent conservateur
    Without preservative
    Stock
    -20 °C,-80 °C
  • Antigène
    CD14
    Autre désignation
    CD14 (CD14 Produits)
    Synonymes
    anticorps CD14 molecule, anticorps CD14 antigen, anticorps CD14, anticorps Cd14
    Sujet
    Background: biG 53 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.
    ID gène
    12475
    NCBI Accession
    NP_033971
    UniProt
    P10810
    Pathways
    Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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