MAF anticorps

N° du produit ABIN346927

Détail du produit anti-MAF anticorps

Antigène: MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAF est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoelectron Microscopy (IEM)

Specificité: Reacts with human 47 kDa Maf protein derived from a transfected CEFcell line

Purification: Antiserum

Immunogène: Maf-GST fusion protein

Isotype: IgG

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
-IHC : 1/50 to 1/500 - WB : 1/200 to 1/5 000 Useful for electrophoretic mobility shift assay (EMSA)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 24 months

Détails sur MAF

Antigène: MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))

Autre désignation: Transcription Factor Maf (MAF Produits)

Synonymes: anticorps MAF, anticorps DKFZp459D1731, anticorps 2810401A20Rik, anticorps A230108G15Rik, anticorps AW047063, anticorps c-maf, anticorps CCA4, anticorps c-MAF, anticorps Maf2, anticorps cMaf, anticorps Z-cmaf, anticorps c-Maf, anticorps fl13d12, anticorps wu:fl13d12, anticorps C-Maf, anticorps MAF bZIP transcription factor, anticorps v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian), anticorps avian musculoaponeurotic fibrosarcoma oncogene homolog, anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a), anticorps MAF, anticorps Maf, anticorps mafa

Sujet: Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element.

NCBI Accession: NP_001026974

UniProt: O75444