HMGB1 anticorps (meLys42, N-Term)
Aperçu rapide pour HMGB1 anticorps (meLys42, N-Term) (ABIN347109)
Antigène
Voir toutes HMGB1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- meLys42, N-Term
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Specificité
- Reacts with HMGB1 methylated on Lysine 42 from human neutrophils
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Réactivité croisée (Details)
- Not tested in other species. May cross react with a wide range of species due to sequence homology.
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Purification
- Antiserum
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Immunogène
- Synthetic peptide derived from N terminal region of HMGB1, containing mono-methyl at K42
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Isotype
- IgG
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Indications d'application
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC1:100 - 1:1000 WB1:200 -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Must be reconstituted in distilled water.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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Date de péremption
- 24 months
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- HMGB1 (High Mobility Group Box 1 (HMGB1))
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Autre désignation
- HMGB1
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Sujet
- HMGB1 is a DAMP involved in innate immune response. It is secreted by activated dendritic cells, macrophages and necrotic cells.
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ID gène
- 3146
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UniProt
- P09429
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Pathways
- Signalisation p53, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome
Antigène
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