KCNQ4 anticorps (N-Term)

N° du produit ABIN347255

Détail du produit anti-KCNQ4 anticorps

Antigène: KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNQ4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Reacts with KCNQ4 from human, mouse and rat protein

Purification: Antiserum

Immunogène: Synthetic peptide derived from Nter domain of KCNQ4 protein

Isotype: IgG

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC(1:100 - 1:1000) WB(1:500 - 1:5000)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 24 months

Détails sur KCNQ4

Antigène: KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))

Autre désignation: Potassium Voltage-Gated Channel Subfamily KQT Member 4, KCNQ4 (KCNQ4 Produits)

Synonymes: anticorps KCNQ4, anticorps k(v)7.4, anticorps kv7.4, anticorps DFNA2, anticorps DFNA2A, anticorps KV7.4, anticorps potassium voltage-gated channel subfamily Q member 4, anticorps potassium channel, voltage gated KQT-like subfamily Q, member 4, anticorps potassium voltage-gated channel, subfamily Q, member 4, anticorps KCNQ4, anticorps kcnq4, anticorps Kcnq4

Sujet: Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinnic receptors

UniProt: P56696

Pathways: Sensory Perception of Sound