IHC, WB. A concentration of 10-50 μg,ml recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Conseil sur la manipulation
Avoid freeze and thaw cycles.
Stock
4 °C/-20 °C
Stockage commentaire
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Date de péremption
12 months
Antigène
Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 6 (SLC17A6)
anticorps 2900073D12Rik, anticorps DNPI, anticorps VGLUT2, anticorps VGluT2, anticorps Dnpi, anticorps Vglut2, anticorps VGLUT2.1, anticorps blu, anticorps si:packt73.2, anticorps si:packt90.2, anticorps si:xx-packt73.2, anticorps slc17a6, anticorps vglut2a, anticorps solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, anticorps solute carrier family 17 member 6, anticorps solute carrier family 17 (vesicular glutamate transporter), member 6b, anticorps Slc17a6, anticorps SLC17A6, anticorps slc17a6b
Sujet
FUNCTION: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane, Multi-pass membrane protein. Cell junction, synapse, synaptosome. TISSUE SPECIFICITY: Expressed in brain. Expressed in hippocampal neurons (at protein level). DEVELOPMENTAL STAGE: Expressed in brain throughout development. Transiently expressed in hippocampal neurons during the first week after birth, with expression decreasing thereafter. MISCELLANEOUS: Mice lacking this protein exhibit an elevated rate of perinatal lethality. Surviving animals display a strong reduction in evoked glutamergic responses in thalamic neurons. Reduction of protein level in homozygous and heterozygous knockouts leads to a graded reduction in the amplitude of the postsynaptic response to single vesicle fusion in thalamic neurons, consistent with a role for this protein in determining quantal size.,SLC17 Family,Vesicular glutamate transporter 2, VGlU2, Solute carrier family 17 member 6, Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter, Differentiation-associated BNPI, Slc17a6, Dnpi