SULT2A1 anticorps (C-Term)

N° du produit ABIN357808

Détail du produit anti-SULT2A1 anticorps

Antigène: SULT2A1 (Sulfotransferase Family, Cytosolic, 2A, Dehydroepiandrosterone (DHEA)-Preferring, Member 1 (SULT2A1))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SULT2A1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects SULT2A (C-term).

Purification: Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SULT2A.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western Blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur SULT2A1

Antigène: SULT2A1 (Sulfotransferase Family, Cytosolic, 2A, Dehydroepiandrosterone (DHEA)-Preferring, Member 1 (SULT2A1))

Autre désignation: SULT2A1 / HST (SULT2A1 Produits)

Synonymes: anticorps dhea-st, anticorps dheas, anticorps st2, anticorps st2a1, anticorps st2a3, anticorps sta, anticorps std, anticorps SULT2A1, anticorps ST2A1, anticorps Std, anticorps Sth1, anticorps mSTa1, anticorps STa, anticorps Smp-2, anticorps St2, anticorps St2a1, anticorps Sth2, anticorps DHEA-ST, anticorps DHEAS, anticorps HST, anticorps ST2, anticorps ST2A3, anticorps STD, anticorps hSTa, anticorps sulfotransferase family 2A member 1, anticorps sulfotransferase family 2A member 1 L homeolog, anticorps alcohol sulfotransferase, anticorps sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1, anticorps SULT2A1, anticorps sult2a1.L, anticorps PCC8801_2155, anticorps Cyan8802_2217, anticorps NAL212_1203, anticorps sult2a1, anticorps Sult2a1

Sujet: One of the major roles of the sulfotransferases (ST) in the metabolism of drugs and endogenous compounds is the conversion of these substances into more hydrophilic water-soluble sulfate conjugates that can be easily excreted. Sulfation may also play a regulatory role for many endogenous compounds, such as steroids and neurotransmitters, by altering the biologic properties of these compounds. Otterness et al. (1992), Kong et al. (1992), and Comer et al. (1993) reported the cloning of cDNAs encoding liver dehydroepiandrosterone (DHEA) sulfotransferase. The predicted protein has 285 amino acids. Although Northern blot analysis of human liver RNA detected transcripts of 3 different sizes, Southern blot analysis of human DNA suggested that only 1 gene is present in the genome. This gene has an important role in the sulfation of both bile acids and steroids in the liver and adrenals. The human adrenal form of this enzyme is physically, immunologically, and kinetically similar, perhaps identical, to the liver form. Dehydroepiandrosterone sulfate is quantitatively one of the major steroids secreted from the adrenal cortex.Synonyms: Bile salt sulfotransferase, DHEA-ST, Dehydroepiandrosterone sulfotransferase, Hydroxysteroid Sulfotransferase, ST2A1, Sulfotransferase 2A1

Poids moléculaire: 33648 Da

ID gène: 6822, 9606

UniProt: Q06520

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process