CYP17A1 anticorps (Middle Region)

N° du produit ABIN360245

Détail du produit anti-CYP17A1 anticorps

Antigène: CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP17A1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to CYP17A1.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human CYP17A1.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur CYP17A1

Antigène: CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))

Autre désignation: CYP17A1 (CYP17A1 Produits)

Synonymes: anticorps cyp17, anticorps CYPXVII, anticorps P450c17, anticorps cyp17a1, anticorps P450-C17, anticorps wu:fi13g04, anticorps wu:fi17b11, anticorps wu:fi31c08, anticorps zgc:136516, anticorps zgc:66494, anticorps P45017A1, anticorps CYP17, anticorps CPT7, anticorps P450C17, anticorps S17AH, anticorps Cyp17, anticorps p450c17, anticorps cytochrome P450 17A1, anticorps cytochrome P450, family 17, subfamily A, polypeptide 1, anticorps steroidogenic cytochrome P450 17-hydroxylase/lyase, anticorps cytochrome P450 family 17 subfamily A member 1 L homeolog, anticorps cytochrome P450 family 17 subfamily A member 1, anticorps cytochrome P-450 17 alpha-hydroxylase/C17,20-lyase, anticorps cytochrome P450, family 17, subfamily a, polypeptide 1, anticorps cytochrome P450c17, anticorps CpipJ_CPIJ010537, anticorps CpipJ_CPIJ010543, anticorps PTRG_02047, anticorps cyp17a1, anticorps cyp17, anticorps cyp17a1.L, anticorps CYP17A1, anticorps Cyp17a1

Sujet: CYP17A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in CYP17A1 gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.Synonyms: 20 lyase, CYP17, CYPXVII, Cytochrome P450 17A1, P450-C17, P450c17, S17AH, Steroid 17-alpha-hydroxylase/17, Steroid 17-alpha-monooxygenase

ID gène: 1586, 9606

UniProt: P05093

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin