IL4 Receptor anticorps (Extracellular Domain)

N° du produit ABIN360908

L’anticorps Rat Monoclonal anti-IL4 Receptor a été validé pour WB. Il convient pour détecter IL4 Receptor dans des échantillons de Souris.

Aperçu rapide pour IL4 Receptor anticorps (Extracellular Domain) (ABIN360908)

Antigène: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL4 Receptor est non-conjugé

Application: Western Blotting (WB)

Clone: 16F23

Détail du produit anti-IL4 Receptor anticorps

Épitope: Extracellular Domain

Specificité: This antibody detects IL-4R.

Purification: Protein A/G affinity chromatography

Immunogène: Recombinant protein of IL-4R extracellular domain.

Isotype: IgG2

Information d'application

Indications d'application: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IL4 Receptor

Antigène: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Autre désignation: CD124 / IL4R

Sujet: The Interleukin-4 receptor is a complex consisting of two chains. One chain is the high affinity IL-4 binding (p140, a chain, CD 124) chain and the other chain is the gamma chain. The high affinity IL-4 binding chain belongs to the cytokine receptor superfamily. The cytoplasmic domain contains Ser/Pro-rich regions similar to those present in the IL-2 receptor and GM-CSF receptor ß-chains. The recombinant human IL-4 soluble receptor corresponds to the human IL-4 receptor extracellular domain. The recombinant, human IL-4 sR is a potent IL-4 antagonist. This antibody will block IL-4 binding to its receptor.Synonyms: 582J2.1, IL-4R-alpha, IL4 Receptor alpha, IL4RA, Interleukin-4 receptor alpha chain

ID gène: 16190

NCBI Accession: NP_001008700

UniProt: P16382

Pathways: Signalistation JAK/STAT, Positive Regulation of Immune Effector Process