SLC32A1 anticorps (N-Term)

N° du produit ABIN361418

Détail du produit anti-SLC32A1 anticorps

Antigène: SLC32A1 (Solute Carrier Family 32 (GABA Vesicular Transporter), Member 1 (SLC32A1))

Épitope: N-Term

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC32A1 est non-conjugé

Application: Western Blotting (WB)

Specificité: Specific for the ~53k VGAT protein.

Réactivité croisée: Poulet, Souris, Rat (Rattus)

Homologie: bovine, canine, non-human primate

Purification: Antigen Affinity Purified from Pooled Serum

Immunogène: Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH

Information d'application

Indications d'application: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Stock: -20 °C

Références pour anticorps anti-SLC32A1 (ABIN361418)

Smith, Jung, Jeon, Kim: "Arid1b haploinsufficiency in parvalbumin- or somatostatin-expressing interneurons leads to distinct ASD-like and ID-like behavior." dans: Scientific reports, Vol. 10, Issue 1, pp. 7834, (2020) (PubMed).

Milinkeviciute, Henningfield, Muniak, Chokr, Green, Cramer: "Microglia Regulate Pruning of Specialized Synapses in the Auditory Brainstem." dans: Frontiers in neural circuits, Vol. 13, pp. 55, (2020) (PubMed).

Santos, Fuertes, Short, Donohue, Shao, Quintanilla, Malakzadeh, Cohen-Cory: "DSCAM differentially modulates pre- and postsynaptic structural and functional central connectivity during visual system wiring." dans: Neural development, Vol. 13, Issue 1, pp. 22, (2018) (PubMed).

Rotschafer, Cramer: "Developmental Emergence of Phenotypes in the Auditory Brainstem Nuclei of Fmr1 Knockout Mice." dans: eNeuro, Vol. 4, Issue 6, (2018) (PubMed).

Rotschafer, Marshak, Cramer: "Deletion of Fmr1 alters function and synaptic inputs in the auditory brainstem." dans: PLoS ONE, Vol. 10, Issue 2, pp. e0117266, (2015) (PubMed).

Korn, Koppel, Li, Mehta, Mehta, Seidl, Cramer: "Astrocyte-secreted factors modulate the developmental distribution of inhibitory synapses in nucleus laminaris of the avian auditory brainstem." dans: The Journal of comparative neurology, (2011) (PubMed).

Détails sur SLC32A1

Antigène: SLC32A1 (Solute Carrier Family 32 (GABA Vesicular Transporter), Member 1 (SLC32A1))

Autre désignation: SLC32A1 (SLC32A1 Produits)

Synonymes: anticorps VGAT, anticorps VIAAT, anticorps vGAT, anticorps Ci-vGAT, anticorps slc32a1, anticorps viaat, anticorps MGC68938, anticorps vgat, anticorps xVIAAT, anticorps R75019, anticorps Viaat, anticorps CG8394, anticorps CG8394.2, anticorps Dmel\\CG8394, anticorps Vgat, anticorps zgc:158324, anticorps solute carrier family 32 member 1, anticorps vesicular GABA transporter, anticorps solute carrier family 32 member 1 S homeolog, anticorps vesicular inhibitory amino acid transporter, anticorps Vesicular inhibitory amino acid transporter, anticorps solute carrier family 32 (GABA vesicular transporter), member 1, anticorps Vesicular GABA Transporter, anticorps SLC32A1, anticorps vgat, anticorps Bm1_20950, anticorps slc32a1.S, anticorps slc32a1, anticorps CpipJ_CPIJ002704, anticorps viaat, anticorps Slc32a1, anticorps VGAT, anticorps Tsp_04599

Sujet: The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles(McIntire et al., 1997). The VGAT protein (also known as the Vesicular Inhibitory Amino Aid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998). Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005). Anti-Vesicular GABA Transporter (VGAT) Western blot of rat hippocampal lysate showing specific immunolabeling of the ~53k VGAT protein.

Poids moléculaire: '53 kDa

ID gène: 83612

UniProt: O35458

Pathways: Proton Transport