mGluR2/3 anticorps (C-Term)

N° du produit ABIN361454

Détail du produit anti-mGluR2/3 anticorps

Antigène: mGluR2/3 (GRIA2/3) (Glutamate Receptor, Ionotropic, AMPA 2/3 (GRIA2/3))

Épitope: C-Term

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp mGluR2/3 est non-conjugé

Application: Western Blotting (WB)

Specificité: Specific for the ~100k GluR2/3 protein.

Réactivité croisée: Rat (Rattus)

Homologie: chicken, human, mouse, zebra fish

Purification: Antigen Affinity Purified from Pooled Serum

Immunogène: Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH

Information d'application

Indications d'application: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Stock: -20 °C

Détails sur mGluR2/3

Antigène: mGluR2/3 (GRIA2/3) (Glutamate Receptor, Ionotropic, AMPA 2/3 (GRIA2/3))

Autre désignation: GRIA2/3 (GRIA2/3 Produits)

Synonymes: anticorps glutamate ionotropic receptor AMPA type subunit 2, anticorps GRIA2

Sujet: The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by (-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990,Hollmann and Heinemann, 1994). The GluR2 subunit is widely expressed throughout the nervous system where it is thought to play key roles in synaptic plasticity and learning and memory (Duprat et al., 2003,Seidenman et al., 2003,Chung et al., 2003,Yan et al., 2002). Anti-GluR2/3 Western blot of rat hippocampal lysate showing specific immunolabeling of the ~100k GluR2/3 protein.

Poids moléculaire: '100 kDa

ID gène: 29627

UniProt: P19491