PTGDS anticorps

N° du produit ABIN363611

Détail du produit anti-PTGDS anticorps

Antigène: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTGDS est non-conjugé

Application: Western Blotting (WB)

Specificité: Reacts with Prostaglandin D Synthase from human, mouse, rat, bovine, canine, feline, primate and rabbit

Purification: Antigen affinity purified

Immunogène: The epitope recognized by this antibody maps to region within residue 120-190 of human PTGDS

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 2 μg/mL

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, glycerol 30 % , Sodium azide 0.1 %

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 6 months

Détails sur PTGDS

Antigène: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Autre désignation: Prostaglandin D Synthase (PTGDS) (PTGDS Produits)

Synonymes: anticorps 6PGD, anticorps GSTS, anticorps GSTS1-1, anticorps PGD2, anticorps PGDS, anticorps L-PGDS, anticorps LPGDS, anticorps PDS, anticorps PGDS2, anticorps H-PGDS, anticorps Ptgds2, anticorps 21kDa, anticorps Ptgs3, anticorps PH2DISO, anticorps phosphogluconate dehydrogenase, anticorps hematopoietic prostaglandin D synthase, anticorps prostaglandin D2 synthase, anticorps prostaglandin D2 synthase (brain), anticorps prostaglandin D synthase, anticorps prostaglandin D2 synthase 21kDa (brain), anticorps PGD, anticorps HPGDS, anticorps PTGDS, anticorps Hpgds, anticorps Ptgds, anticorps LOC100009453

Sujet: The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. PTGDS has also been implicated in the development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement (NREM) sleep. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. PTGDS is the most abundant protein in the cerebral spinal fluidand recent evidence suggests that PTGDS acts as a Beta-Amyloid chaperone and may have a role in the deposition of Ab plaques in Alzheimer's disease.