MYL2 anticorps (N-Term)

N° du produit ABIN371883

Détail du produit anti-MYL2 anticorps

Antigène: MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))

Épitope: AA 1-166, N-Term

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MYL2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: The antibody recognizes Human and Rat MYL2 (1-166). Other species not tested.

Attributs du produit: Synonyms: MLC-2v, MLC-2, Myosin regulatory light chain 2 ventricular/cardiac muscle isoform

Purification: Protein-G affinity chromatography

Immunogène: Recombinant Human MYL2 (1-166 aa) purified from E. coli

Clone: AT3B2

Isotype: IgG2b

Information d'application

Indications d'application: ELISA. Western blot (1/1,000-1/2,000). Immunohistochemistry on Paraffin Sections (5 μg/mL). This MYL2 antibody was validatedfor use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE)human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubationwith the primary antibody, slides were incubated with biotinylated secondary antibody,followed by alkaline phosphatase-streptavidin and chromogen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur MYL2

Antigène: MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))

Autre désignation: Myosin Light Chain 2 (MYL2) (MYL2 Produits)

Synonymes: anticorps CMH10, anticorps MLC2, anticorps 2410014J02Rik, anticorps MLC-2, anticorps Mlc2, anticorps MLC-2v, anticorps Mlc2v, anticorps Mylpc, anticorps Mlc-2, anticorps myl2, anticorps zgc:136848, anticorps XMLC2, anticorps cmh10, anticorps mlc2, anticorps G2, anticorps MLC-2A, anticorps MLC2V, anticorps myosin light chain 2, anticorps myosin light chain, phosphorylatable, fast skeletal muscle, anticorps myosin, light polypeptide 2, regulatory, cardiac, slow, anticorps myosin, light chain 2b, regulatory, cardiac, slow, anticorps myosin light chain 2 S homeolog, anticorps myosin, light chain 2, regulatory, cardiac, slow, anticorps MYL2, anticorps Mylpf, anticorps Myl2, anticorps myl2b, anticorps myl2.S

Sujet: Myosin light chain 2 (MYL2) encodes the regulatory light chain associated with cardiac myosin beta heavy chain. It is an important protein involved in the regulation of myosin ATPase activity in smooth muscle and Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.Synonyms: MLC-2, MLC-2v, Myosin regulatory light chain 2 ventricular/cardiac muscle isoform

ID gène: 4633

UniProt: P10916

Pathways: Myometrial Relaxation and Contraction