MARCH4 anticorps (AA 300-350)

N° du produit ABIN372267

Détail du produit anti-MARCH4 anticorps

Antigène: MARCH4 (Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase (MARCH4))

Épitope: AA 300-350

Reactivité: Humain, Souris, Rat, Chien, Poulet, Cheval, Opossum, Poisson zèbre (Danio rerio), Chimpanzé

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MARCH4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody recognizes Membrane-Associated Ring Finger 4 (MARCH4).

Réactivité croisée (Details): Species reactivity (expected):Chimpanzee, Chicken, Dog (Canine), Horse, Mouse, Opossum, Rat and ZebrafishSpecies reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogène: Synthetic peptide corresponding to a portion of the amino acids 300-350 of human RNF174.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western Blot: 0.5-2.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % Sodium Azide as preservative and 0.05 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur MARCH4

Antigène: MARCH4 (Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase (MARCH4))

Autre désignation: MARCH4 / RNF174 (MARCH4 Produits)

Synonymes: anticorps MARCH-IV, anticorps RNF174, anticorps BC056494, anticorps mKIAA1399, anticorps MARCH4, anticorps si:ch211-239d11.2, anticorps membrane associated ring-CH-type finger 4, anticorps membrane-associated ring finger (C3HC4) 4, anticorps MARCH4, anticorps March4, anticorps march4

Sujet: MARCH4, an E3 ubiquitin protein ligase, may mediate ubiquitination of MHC I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin protein ligases accept ubiquitin from an E2 ubiquitin conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.Synonyms: E3 ubiquitin-protein ligase MARCH4, KIAA1399, MARCH-IV, Membrane-associated RING finger protein 4, Membrane-associated RING-CH protein IV, RING finger protein 174

Poids moléculaire: 46 kDa

ID gène: 57574

NCBI Accession: NP_065865

UniProt: Q9P2E8