IPO7 anticorps (C-Term)

N° du produit ABIN374249

Détail du produit anti-IPO7 anticorps

Antigène: IPO7 (Importin 7 (IPO7))

Épitope: C-Term

Reactivité: Humain, Souris, Boeuf (Vache), Rat, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp IPO7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: C-SSFNFGGPAP GMN

Specificité: This antibody detects RanBP7/Importin-7 at C-term.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Dog, CowSpecies reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogène: Synthetic peptide from C-terminus of Human IPO7 (NP_006382.1). Genename: IPO7

Information d'application

Indications d'application: Peptide ELISA: Limit dilution: 1/32000. Western blot: 0.1-1 μg/mL. Approx 120 kDa band observed in Human Brain lysates(predicted MW of 110 kDa according to NP_006382.1). Please note that an approx 30 kDaband of unknown identity is also consistently observed. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing of 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IPO7

Antigène: IPO7 (Importin 7 (IPO7))

Autre désignation: RanBP7 / Importin-7 (IPO7 Produits)

Synonymes: anticorps fb33d09, anticorps wu:fb33d09, anticorps zgc:66425, anticorps zgc:76878, anticorps imp7, anticorps ranbp7, anticorps Imp7, anticorps RANBP7, anticorps A330055O14Rik, anticorps C330016G14, anticorps Ranbp7, anticorps importin 7, anticorps importin 7 S homeolog, anticorps importin-7, anticorps karyopherin, anticorps ipo7, anticorps ipo7.S, anticorps IPO7, anticorps CpipJ_CPIJ002096, anticorps PTRG_08544, anticorps SJAG_03693, anticorps NAEGRDRAFT_71372, anticorps VDBG_01971, anticorps MGYG_08162, anticorps Tsp_01943, anticorps Tsp_01946, anticorps Ipo7

Sujet: The Importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran binding site of importin beta. Similar to importin beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta like transport receptors, namely importin beta itself, transportin, RanBP5 and Importin 7, directly bind and import ribosomal proteins.Synonyms: IMP7, IPO7, Ran-binding protein 7

ID gène: 10527

NCBI Accession: NP_006382

UniProt: O95373

Pathways: Protein targeting to Nucleus