Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (C-Term) anticorps

N° du produit ABIN374273

Détail du produit

Antigène: Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial

Épitope: C-Term

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Séquence: C-RLIVAREHID KYKN

Specificité: This antibody detects ACADM at C-term. Expected to recognise both reported isoforms.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Synthetic peptide from C-Terminus of Human ACADM protein (NP_000007.1, NP_001120800.1) Genename: ACADM

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détail du antigène

Antigène: Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial

Autre désignation: ACADM

Synonymes: anticorps ACAD1, anticorps MCAD, anticorps MCADH, anticorps AU018656, anticorps acyl-CoA dehydrogenase medium chain, anticorps acyl-Coenzyme A dehydrogenase, medium chain, anticorps acyl-CoA dehydrogenase, C-4 to C-12 straight chain, anticorps ACADM, anticorps Acadm

Sujet: ACADM protein is a medium chain specific (C4 to C12 straight chain) acyl Coenzyme A dehydrogenase. The enzyme catalyzes the initial step of the mitochondrial fatty acid beta oxidation pathway. ACADM expression is induced during periods of fasting, when reliance on fatty acids for energy is increased. Clinical phenotypes are associated with ACADM hereditary deficiency.Synonyms: MCAD, Medium-chain specific acyl-CoA dehydrogenase mitochondrial

ID gène: 34

NCBI Accession: NP_000007

UniProt: P11310