NEIL1 anticorps (C-Term)

N° du produit ABIN374304

Détail du produit anti-NEIL1 anticorps

Antigène: NEIL1 (Endonuclease VIII-Like 1 (NEIL1))

Épitope: C-Term

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp NEIL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Séquence: C-DIPSLEPEGT SAS

Specificité: This antibody detects NEIL1 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from C Terminus of the protein sequence according to NP_078884.2 Genename: NEIL1

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1: 16000. Western blot: Experiments gave an approx 60 kDa band in Human Liver and Brain lysates at1 μg/mL. Immunohistochemistry: 5-10 μg/mL. In paraffin embedded Human Placenta shows strongstaining of cytoplasm in syncytiotrophoblasts.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Détails sur NEIL1

Antigène: NEIL1 (Endonuclease VIII-Like 1 (NEIL1))

Autre désignation: NEIL1 (NEIL1 Produits)

Synonymes: anticorps FPG1, anticorps NEI1, anticorps hFPG1, anticorps 2810450N13Rik, anticorps Nei1, anticorps nei-like DNA glycosylase 1, anticorps nei like DNA glycosylase 1, anticorps nei endonuclease VIII-like 1 (E. coli), anticorps Neil1, anticorps NEIL1

Sujet: Human NEIL1 is the homologs of Escherichia coli Nei. Human NEIL1 is a DNA glycosylase, that phylogenetically belongs to the Fpg/Nei family, primarily found in the bacterial kingdom and is functionally homologous to bacterial Nei. Thymine glycol, a potentially lethal DNA lesion produced by reactive oxygen species, can be removed by DNA glycosylases. The NEIL1 gene is located on the long arm of chromosome 15 that is frequently deleted in human cancers.Synonyms: DNA glycosylase/AP lyase Neil1, DNA-(apurinic or apyrimidinic site) lyase Neil1, Endonuclease VIII-like 1, FPG1, NEH1

ID gène: 79661

NCBI Accession: NP_078884

UniProt: Q96FI4

Pathways: Réparation de l'ADN