Coronin 1a anticorps (C-Term)

N° du produit ABIN374350

Détail du produit anti-Coronin 1a anticorps

Antigène: Coronin 1a (CORO1A) (Coronin, Actin Binding Protein, 1A (CORO1A))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Coronin 1a est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: C-KRLDRLEETV QAK

Specificité: This antibody detects Coronin-1A / TACO at C-term.

Réactivité croisée (Details): Species reactivity (expected):Rat, Canine (Dog), Cow.
Species reactivity (tested):Human, Mouse.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide from the C-Terminus of the protein sequence according to NP_009005.1 Genename: CORO1A

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1: 16000. Western blot: 0.25-1 μg/mL. Approx 60 kDa band observed in Molt-4 and Jurkat lysates(predicted MW of 50 kDa according to NP_009005.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Coronin 1a

Antigène: Coronin 1a (CORO1A) (Coronin, Actin Binding Protein, 1A (CORO1A))

Autre désignation: Coronin-1A (CORO1A Produits)

Synonymes: anticorps CORO1A, anticorps cor1a, anticorps Clabp, anticorps Lmb3, anticorps TACO, anticorps p57, anticorps CLABP, anticorps CLIPINA, anticorps HCORO1, anticorps fj83g12, anticorps wu:fj83g12, anticorps zgc:63766, anticorps coronin 1A, anticorps Coronin-1A, anticorps coronin, actin binding protein 1A, anticorps coronin, actin binding protein, 1A, anticorps CORO1A, anticorps cor1a, anticorps Coro1a, anticorps coro1a

Sujet: Coronin 1a belongs to the WD repeat coronin family and contains 5 WD repeats. It may be an essential component of the cytoskeleton of highly motile cells, with roles both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In cell infected by mycobacteria, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes. In the CNS, coronin 1A is expressed exclusively by microglial cells. Although its function is not entirely clear, it may act as a linkage protein between the actin cytoskeleton and the plasma membrane, and perhaps the extracellular matrix.Synonyms: CORO1, CORO1A, Clipin-A, Coronin-like protein, Coronin-like protein p57, TACO, Tryptophan aspartate-containing coat protein

ID gène: 11151

NCBI Accession: NP_009005

UniProt: P31146

Pathways: Regulation of Actin Filament Polymerization