ARHGEF4 anticorps (N-Term)

N° du produit ABIN374361

Cet anticorps anti-ARHGEF4 Polyclonal Chèvre (ABIN374361) détecte spécifiquement ARHGEF4 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ARHGEF4 anticorps (N-Term) (ABIN374361)

Antigène: ARHGEF4 (rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ARHGEF4 anticorps

Épitope: N-Term

Séquence: PWEEPAGEKP SCS

Specificité: This antibody detects ARHGEF4 at N-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from N Terminus of the protein sequence according to NP_056135.2, NP_127462.1. Genename: ARHGEF4

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1: 32000. Western blot: 2-4 μg/mL. Approx 80 kDa band observed in Human Brain lysates and intransfected HEK293 transiently expressing ARHGEF4 (calculated MW of 79.0 kDa accordingto NP_056135.2 and 76.0 kDa according to 127462.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Détails sur ARHGEF4

Antigène: ARHGEF4 (rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4))

Autre désignation: ARHGEF4

Sujet: ARHGEF4 may form complexes with G proteins and stimulate Rho-dependent signals, and is similar to rat collybistin protein. Rho GTPases play a fundamental role in numerous cellular processes, which are initiated by extracellular stimuli that work through G protein coupled receptors. Alternative splicing of this gene generates two transcript variants which encode different isoforms.Synonyms: APC-stimulated guanine nucleotide exchange factor, ASEF, KIAA1112, Rho guanine nucleotide exchange factor 4

ID gène: 50649

NCBI Accession: NP_056135

UniProt: Q9NR80

Pathways: Neurotrophin Signaling Pathway