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SNTA1 anticorps (N-Term)

SNTA1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc WB, EIA Hôte: Chèvre Polyclonal unconjugated
N° du produit ABIN374379
  • Antigène Voir toutes SNTA1 Anticorps
    SNTA1 (Syntrophin, alpha 1 (Dystrophin-Associated Protein A1, 59kDa, Acidic Component) (SNTA1))
    Épitope
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 50
    • 22
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Porc
    Hôte
    • 43
    • 6
    • 1
    Chèvre
    Clonalité
    • 35
    • 15
    Polyclonal
    Conjugué
    • 22
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SNTA1 est non-conjugé
    Application
    • 21
    • 14
    • 14
    • 10
    • 7
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Séquence
    ASGRRAPRTG LLE-C
    Specificité
    This antibody detects Alpha-1-syntrophin (SNTA1) at N-term.
    Réactivité croisée (Details)
    Species reactivity (expected):Dog, Pig, Cow.
    Species reactivity (tested):Human, Mouse, Rat.
    Purification
    Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
    Immunogène
    Peptide from N Terminus of the protein sequence according to NP_003089.1 Genename: SNTA1
    Top Product
    Discover our top product SNTA1 Anticorps primaire
  • Indications d'application
    Peptide ELISA: Detection limit dilution 1: 32000. Western Blot: 1-3 μg/mL. Approx 60 kDa band observed in Human Skeletal Muscle lysates(calculated MW of 53.0 kDa according to NP_003089.1).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.
  • Antigène
    SNTA1 (Syntrophin, alpha 1 (Dystrophin-Associated Protein A1, 59kDa, Acidic Component) (SNTA1))
    Autre désignation
    Syntrophin-1 / SNTA1 (SNTA1 Produits)
    Synonymes
    anticorps SNTA1, anticorps MGC147484, anticorps AW228934, anticorps Snt1, anticorps LQT12, anticorps SNT1, anticorps TACIP1, anticorps dJ1187J4.5, anticorps syntrophin alpha 1, anticorps syntrophin, alpha 1 L homeolog, anticorps syntrophin, alpha 1, anticorps syntrophin, acidic 1, anticorps SNTA1, anticorps snta1.L, anticorps snta1, anticorps Snta1
    Sujet
    Syntrophins are structurally related proteins located at the neuromuscular synapse and play an important role in dystrophin associated protein (DAP) complex formation. To date there have been three distinct syntrophin isoforms discovered: alpha 1, beta 1, and beta 2. These proteins each contain a PDZ domain, a syntrophin-unique domain (SU), and three pleckstrin homology domains (PH1a,1b and 2). The PDZ domain has been shown to be responsible for binding syntrophin to nNOS and the DAP complex. This association results in localization of the nicotinic acetylcholine receptor to the cytoskeleton via the (S/T)XV C terminus.Synonyms: 59 kDa dystrophin-associated protein A1 acidic component 1, Alpha-1-syntrophin, Pro-TGF-alpha cytoplasmic domain-interacting protein 1, SNT1, TACIP1
    ID gène
    6640
    NCBI Accession
    NP_003089
    UniProt
    Q13424
    Pathways
    Synaptic Membrane, Skeletal Muscle Fiber Development
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