GOPC anticorps (C-Term)

N° du produit ABIN374395

Détail du produit anti-GOPC anticorps

Antigène: GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))

Épitope: C-Term

Reactivité: Humain, Boeuf (Vache), Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp GOPC est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: C-LDDLHTLYHK KSY

Specificité: This antibody detects PIST / FIG / GOPC at C-term. It is expected to recognize both reported isoforms.

Réactivité croisée (Details): Species reactivity (expected):Canine (Dog), Cow.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide from C-Terminus of the protein sequence according to NP_065132.1, NP_001017408.1 Genename: GOPC

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1: 128000. Western blot: 0.05-0.2 μg/mL. Approx.55 kDa band observed in Human Brain (FrontalCortex) lysates (calculated MW of 50.5 kDa according to NP_065132.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GOPC

Antigène: GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))

Autre désignation: GOPC / PIST (GOPC Produits)

Synonymes: anticorps DKFZp459H2130, anticorps 2210402P09Rik, anticorps AI844555, anticorps CAL, anticorps FIG, anticorps GOPC1, anticorps PIST, anticorps fe38f01, anticorps wu:fe38f01, anticorps zgc:56254, anticorps zgc:65853, anticorps dJ94G16.2, anticorps cal, anticorps gopc1, anticorps pist, anticorps golgi associated PDZ and coiled-coil motif containing, anticorps golgi-associated PDZ and coiled-coil motif containing, anticorps golgi-associated PDZ and coiled-coil motif containing S homeolog, anticorps GOPC, anticorps Gopc, anticorps gopc, anticorps gopc.S

Sujet: PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner. PIST, a PDZ domain-containing Golgi protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6. Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1.Synonyms: CAL, CFTR-associated ligand, FIG, Fused in glioblastoma, Golgi-associated PDZ and coiled-coil motif-containing protein, PDZ protein interacting specifically with TC10

ID gène: 57120

NCBI Accession: NP_065132

UniProt: Q9HD26

Pathways: Maintenance of Protein Location, Asymmetric Protein Localization