Transgelin anticorps (C-Term)

N° du produit ABIN374407

Détail du produit anti-Transgelin anticorps

Antigène: Transgelin (TAGLN)

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Transgelin est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: C-MTGYGRPRQI IS

Specificité: This antibody detects Transgelin (TAGLN) at C-term.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog), Cow.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence from the C-Terminus of the protein sequence according to NP_003177.2. Genename: TAGLN

Information d'application

Indications d'application: Peptide ELISA: Limit Dilution: 1/32000. Western blot: 0.01-0.03 mg/mL. Approx 24 kDa band observed in Human Placenta Lysates(calculated MW of 22.4 kDa according to NP_003177.2 and NP_001001522.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-Transgelin (ABIN374407)

Epting, Slanchev, Boehlke, Hoff, Loges, Yasunaga, Indorf, Nestel, Lienkamp, Omran, Kuehn, Ronneberger, Walz, Kramer-Zucker: "The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin." dans: Development (Cambridge, England), Vol. 142, Issue 1, pp. 174-84, (2014) (PubMed).

Lee, Uchida, Emoto, Umeda, Kuge, Taguchi, Arai: "Impaired retrograde membrane traffic through endosomes in a mutant CHO cell defective in phosphatidylserine synthesis." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 17, Issue 8, pp. 728-36, (2012) (PubMed).

Huet, Fanget, Jouannot, Meireles, Zeiske, Larochette, Darchen, Desnos: "Myrip couples the capture of secretory granules by the actin-rich cell cortex and their attachment to the plasma membrane." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 7, pp. 2564-77, (2012) (PubMed).

Wang, Chen, Wu, Tsai, Shyue, Yang, Tzeng: "Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury." dans: Journal of biomedical science, Vol. 18, pp. 13, (2011) (PubMed).

Pringle, Zakar, Yates, Mitchell, Hirst, Lumbers: "Molecular evidence of a (pro)renin/ (pro)renin receptor system in human intrauterine tissues in pregnancy and its association with PGHS-2." dans: Journal of the renin-angiotensin-aldosterone system : JRAAS, Vol. 12, Issue 3, pp. 304-10, (2011) (PubMed).

Cencetti, Bernacchioni, Nincheri, Donati, Bruni: "Transforming growth factor-beta1 induces transdifferentiation of myoblasts into myofibroblasts via up-regulation of sphingosine kinase-1/S1P3 axis." dans: Molecular biology of the cell, Vol. 21, Issue 6, pp. 1111-24, (2010) (PubMed).

Yokoe, Toiyama, Okugawa, Tanaka, Ohi, Inoue, Mohri, Miki, Kusunoki: "KAP1 is associated with peritoneal carcinomatosis in gastric cancer." dans: Annals of surgical oncology, Vol. 17, Issue 3, pp. 821-8, (2010) (PubMed).

Nincheri, Luciani, Squecco, Donati, Bernacchioni, Borgognoni, Luciani, Benvenuti, Francini, Bruni: "Sphingosine 1-phosphate induces differentiation of adipose tissue-derived mesenchymal stem cells towards smooth muscle cells." dans: Cellular and molecular life sciences : CMLS, Vol. 66, Issue 10, pp. 1741-54, (2009) (PubMed).

Donoghue, Doran, Wynne, Pedersen, Dunn, Ohlendieck: "Proteomic profiling of chronic low-frequency stimulated fast muscle." dans: Proteomics, Vol. 7, Issue 18, pp. 3417-30, (2007) (PubMed).

Saijou, Itoh, Kim, Iemura, Natsume, Miyajima: "Nucleocytoplasmic shuttling of the zinc finger protein EZI Is mediated by importin-7-dependent nuclear import and CRM1-independent export mechanisms." dans: The Journal of biological chemistry, Vol. 282, Issue 44, pp. 32327-37, (2007) (PubMed).

Nakamura, Moore, Negishi, Sueyoshi: "Nuclear pregnane X receptor cross-talk with FoxA2 to mediate drug-induced regulation of lipid metabolism in fasting mouse liver." dans: The Journal of biological chemistry, Vol. 282, Issue 13, pp. 9768-76, (2007) (PubMed).

Tamimi, Skarie, Footz, Berry, Link, Walter: "FGF19 is a target for FOXC1 regulation in ciliary body-derived cells." dans: Human molecular genetics, Vol. 15, Issue 21, pp. 3229-40, (2006) (PubMed).

Détails sur Transgelin

Antigène: Transgelin (TAGLN)

Abstract: TAGLN Produits

Synonymes: anticorps MGC68550, anticorps sm22, anticorps smcc, anticorps tagln1, anticorps ws3-10, anticorps MGC107855, anticorps SM22, anticorps SMCC, anticorps TAGLN1, anticorps WS3-10, anticorps Sm22, anticorps Sm22a, anticorps Ws310, anticorps SM22A, anticorps zgc:153186, anticorps transgelin L homeolog, anticorps transgelin, anticorps tagln.L, anticorps tagln, anticorps LOC732906, anticorps TAGLN, anticorps tagl, anticorps LOC100009332, anticorps Tagln

Sujet: TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear.Synonyms: 22 kDa actin-binding protein, SM22, Smooth muscle protein 22-alpha, WS3-10

ID gène: 6876

NCBI Accession: NP_003177

UniProt: Q01995