Paired Box 3 anticorps (N-Term)

N° du produit ABIN374426

Détail du produit anti-Paired Box 3 anticorps

Antigène: Paired Box 3 (PAX3)

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Paired Box 3 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: TTLAGAVPRM M-C

Specificité: This antibody detects PAX3 at N-term. This antibody is expected to recognise all 7 reported human isoforms (as represented by NP_000429.2, NP_039230.1, NP_852122.1,.1 NP_852123.1, NP_852124.1, NP_852125.1 and NP_852126.1).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat and Cow.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide from the N Terminus of the protein sequence according to NP_000429.2, NP_039230.1, NP_852122.1,.1 NP_852123.1, NP_852124.1, NP_852125.1, NP_852126.1. Genename: PAX3

Information d'application

Indications d'application: Peptide ELISA: Antibody Limit Dilution: 1/64000. Western blot: Preliminary experiments gave an approx 30-35 kDa band in Human Kidneylysates at 1 μg/mL. Immunohistochemistry: 3 μg/mL. In paraffin embedded Human Oesophagus showsnuclear staining of cells in the Squamous Epithelium.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.

Détails sur Paired Box 3

Antigène: Paired Box 3 (PAX3)

Autre désignation: PAX3 (PAX3 Produits)

Synonymes: anticorps PAX3, anticorps cdhs, anticorps hup2, anticorps pax-3, anticorps ws1, anticorps xpax3, anticorps Pax3, anticorps pax3, anticorps pax3b, anticorps xPax3-B, anticorps CDHS, anticorps HUP2, anticorps WS1, anticorps WS3, anticorps Pax-3, anticorps Sp, anticorps splotch, anticorps zgc:92547, anticorps paired box 3, anticorps paired box 3 L homeolog, anticorps paired box 3a, anticorps PAX3, anticorps pax3, anticorps pax3.L, anticorps Pax3, anticorps pax3a

Sujet: This protein is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These proteins play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.Synonyms: HUP2, Paired box protein Pax-3, Pax-3

ID gène: 5077

NCBI Accession: NP_000429

UniProt: P23760

Pathways: Sensory Perception of Sound, Tube Formation