HPGD anticorps (C-Term)

N° du produit ABIN374495

Détail du produit anti-HPGD anticorps

Antigène: HPGD (Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))

Épitope: C-Term

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp HPGD est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to Prostaglandin dehydrogenase 1.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-DYDTTPFQAKTQ, from the C Terminus of the protein sequence

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur HPGD

Antigène: HPGD (Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))

Autre désignation: HPGD (HPGD Produits)

Synonymes: anticorps CBR, anticorps SDR21C1, anticorps hCBR1, anticorps 15-PGDH, anticorps PGDH, anticorps PGDH1, anticorps PHOAR1, anticorps SDR36C1, anticorps MGC80546, anticorps MGC79454, anticorps AV026552, anticorps carbonyl reductase 1, anticorps 15-hydroxyprostaglandin dehydrogenase, anticorps hydroxyprostaglandin dehydrogenase 15-(NAD), anticorps 15-hydroxyprostaglandin dehydrogenase L homeolog, anticorps hydroxyprostaglandin dehydrogenase 15 (NAD), anticorps CBR1, anticorps HPGD, anticorps hpgd.L, anticorps hpgd, anticorps pgdh, anticorps Hpgd, anticorps PTRG_03214, anticorps VDBG_09957

Sujet: Prostaglandins are involved in many physiologic and cellular processes, such as inflammation. The NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH, type I) is the main enzyme of prostaglandin degradation. By catalyzing the conversion of the 15-hydroxyl group of prostaglandins into a keto group, this ubiquitous enzyme strongly reduces the biologic activity of these molecules. The induction of 15-PGDH expression by dexamethasone and other glucocorticoids at the therapeutic level provides an additional biochemical mechanism for the anti-inflammatory action of these glucocorticoids.Synonyms: 15-hydroxyprostaglandin dehydrogenase, PGDH, PGDH1, Prostaglandin dehydrogenase 1

ID gène: 3248

NCBI Accession: NP_000851

UniProt: P15428