TPI1 anticorps (C-Term)

N° du produit ABIN374519

Détail du produit anti-TPI1 anticorps

Antigène: TPI1 (Triosephosphate Isomerase 1 (TPI1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp TPI1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody is expected to recognise both reported isoforms of Triosephosphate isomerase (TPI1).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine and Bovine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence C-LKPEFVDIINAKQ, from the C Terminus of the protein sequence according to NP_000356.1, NP_001152759.1. Genename: TPI1

Information d'application

Indications d'application: Peptide ELISA: Limit Dilution: 1/16000. Western blot: 0.01-0.03 μg/mL. Approx 26 kDa band observed in human liver and humanhepatoblastoma HepG2 cell lysates (calculated MW of 26.6 kDa according to NP_000356).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TPI1

Antigène: TPI1 (Triosephosphate Isomerase 1 (TPI1))

Autre désignation: Triosephosphate Isomerase (TPI1) (TPI1 Produits)

Synonymes: anticorps TIM, anticorps TPI, anticorps TIM1, anticorps hTIM, anticorps tpi, anticorps tpi1, anticorps TPI1, anticorps AI255506, anticorps Tpi, anticorps Tpi-1, anticorps GB17473, anticorps Tim, anticorps CG2171, anticorps Dmel\\CG2171, anticorps ND14, anticorps TPIS, anticorps sgk, anticorps wstd, anticorps DrTPI-A, anticorps DrTPI-B, anticorps TIM-B, anticorps cb179, anticorps wu:fb51c02, anticorps triosephosphate isomerase 1, anticorps timeless circadian regulator, anticorps triosephosphate isomerase 1 S homeolog, anticorps triosephosphate isomerase, anticorps triose-phosphate isomerase, anticorps Triose-phosphate isomerase, anticorps triose-phosphate isomerase, putative, anticorps timeless circadian clock, anticorps Triose phosphate isomerase, anticorps Triosephosphate isomerase, anticorps triosephosphate isomerase 1a, anticorps triosephosphate isomerase 1b, anticorps TPI1, anticorps TIMELESS, anticorps tpi1, anticorps Tpi1, anticorps tpi1.S, anticorps Tpi, anticorps tpiA, anticorps CNE05000, anticorps Fnod_0738, anticorps Tlet_0996, anticorps SARE_RS16215, anticorps PKH_126640, anticorps Timeless, anticorps tpi-1, anticorps tpi1a, anticorps tpi1b

Sujet: Triosephosphate isomerase (TIM) catalyses the reversible interconversion of G3P and DHAP. Only G3P can be used in glycolysis, therefore TIM is essential for energy production, allowing two molecules of G3P to be produced for every glucose molecule, thereby doubling the energy yield. Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) [MIM:190450]. TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection.Synonyms: TIM, TPI, Triose-phosphate isomerase

ID gène: 7167, 9606

UniProt: P60174

Pathways: Cell RedoxHomeostasis