STX1A anticorps (N-Term)

N° du produit ABIN374595

Détail du produit anti-STX1A anticorps

Antigène: STX1A (Syntaxin 1A (Brain) (STX1A))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp STX1A est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: KDRTQELRTA KD-C

Specificité: Please note this product is expected to recognize the products of 2 different genes STX1A (NP_004594.1and NP_001159375.1) and STX1B (NP_443106.1).

Réactivité croisée (Details): Species reactivity (expected):Human, Rat, Canine, Bovine.
Species reactivity (tested):Mouse.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence from the N Terminus of the protein sequence according to NP_004594.1, NP_001159375.1, NP_443106.1.

Information d'application

Indications d'application: Peptide ELISA: 1/32000. Western Blot: 0.01 - 0.03 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur STX1A

Antigène: STX1A (Syntaxin 1A (Brain) (STX1A))

Autre désignation: Syntaxin 1A / STX1A (STX1A Produits)

Synonymes: anticorps HPC-1, anticorps P35-1, anticorps STX1, anticorps SYN1A, anticorps STX1A, anticorps hpc-1, anticorps p35-1, anticorps stx1, anticorps sx1a, anticorps syntaxin1a, anticorps CG10716, anticorps CG18615, anticorps CG31136, anticorps CG5448, anticorps CT30033, anticorps Dm Syx1, anticorps DmSyx1A, anticorps Dmel\\CG31136, anticorps SYX1A, anticorps Syt1A, anticorps Syx, anticorps Syx-1A, anticorps Syx1, anticorps Syx1a, anticorps SyxA, anticorps anon-EST:Gibbs4, anticorps anon-WO02059370.54, anticorps dSyx1, anticorps l(3)06737, anticorps synt, anticorps syt-1A, anticorps syx, anticorps syx-1, anticorps syx-1A, anticorps syx1, anticorps syx1A, anticorps syntaxin 1A, anticorps syntaxin 1A (brain), anticorps Syntaxin 1A, anticorps syntaxin-1A, anticorps STX1A, anticorps Stx1a, anticorps stx1a, anticorps Syx1A, anticorps EDI_005240, anticorps Tsp_07354

Sujet: Syntaxin is a 35 kDa type II integral membrane protein localized to the plasma membrane at nerve terminals. Syntaxin was identified through its association with synaptotagmin and N-type calcium channel, a subtype of calcium channel on the plasma membrane important for neurotransmitter release. Homologs of syntaxin were identified in various eukaryotes ranging from yeast to human. Evidences for syntaxin's involvement in vesicular transport and neurotransmission include the requirement of its yeast homologs, SSO 1 and 2, in targeting and fusion of Golgi-derived vesicles with the plasma membrane. Syntaxin is also the target of clostridial neurotoxin C1 that block neurotransmitter release. The formation of 20S complex involves the interaction of VAMP with syntaxin through an ATP-dependent reaction modulated by synaptotagmin, SNAP-25, alpha-SNAP, and NSF.Synonyms: Neuron-specific antigen HPC-1, STX1, STX1B1, STX1B2, Syntaxin-1A, Syntaxin-1B, Syntaxin-1B1, Syntaxin-1B2

ID gène: 6804

NCBI Accession: NP_001159375

UniProt: Q16623

Pathways: Peptide Hormone Metabolism, Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport