NONO anticorps (C-Term)

N° du produit ABIN374683

Détail du produit anti-NONO anticorps

Antigène: NONO (Non-POU Domain Containing, Octamer-Binding (NONO))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp NONO est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: C-NRAAPGAEFA PNK

Specificité: This antibody recognizes NONO / NMT55.

Réactivité croisée (Details): Species reactivity (expected):Rat, Canine.
Species reactivity (tested):Human, Mouse.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence from the C Terminus of the protein sequence (NP_031389.3). Genename: NONO

Information d'application

Indications d'application: Peptide ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur NONO

Antigène: NONO (Non-POU Domain Containing, Octamer-Binding (NONO))

Autre désignation: NONO / NMT55 (NONO Produits)

Synonymes: anticorps NMT55, anticorps NRB54, anticorps P54, anticorps P54NRB, anticorps nmt55, anticorps nrb54, anticorps p54nrb, anticorps xp54nrb, anticorps AA407051, anticorps AV149256, anticorps nonA, anticorps non-POU domain containing octamer binding, anticorps non-POU domain containing, octamer-binding, anticorps non-POU domain containing, octamer binding L homeolog, anticorps non-POU-domain-containing, octamer binding protein, anticorps NONO, anticorps Nono, anticorps nono.L

Sujet: Nmt55/p54nrb is a DNA and RNA binding protein that has been implicated in multiple cellular functions such as regulation of cell division as well as cancer biology. Expression of this protein has been found to be decreased in some human breast tumors, and has been studied as a relevant tumor marker. It has been found that decreased nmt55/p54nrb expression in Estrogen Receptor (ER)-negative human breast tumors or the expression of nmt55/p54nrb variants in ER-positive tumors may indicate the loss of normal growth. It is possible that nmt55/p54nrb acts as a pre-mRNA splicing factor affecting the structure and function of hERalpha.Synonyms: NRB54

ID gène: 4841

NCBI Accession: NP_001138880

UniProt: Q15233