STAG2 anticorps (Internal Region)

N° du produit ABIN374783

Détail du produit anti-STAG2 anticorps

Antigène: STAG2 (Stromal Antigen 2 (STAG2))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp STAG2 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody is expected to recognise isoform a and isoform b of STAG2.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-REPKRLRPEDS, from the internal region of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/128000. Western Blot: 0.01 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur STAG2

Antigène: STAG2 (Stromal Antigen 2 (STAG2))

Autre désignation: STAG2 / Stromal Antigen 2 (STAG2 Produits)

Synonymes: anticorps SA-2, anticorps SA2, anticorps SCC3B, anticorps bA517O1.1, anticorps RGD1562042, anticorps STAG2, anticorps stag2, anticorps 9230105L23Rik, anticorps B230112I07Rik, anticorps SAP2, anticorps XSA2, anticorps sa2, anticorps sa2-a, anticorps stromal antigen 2, anticorps cohesin subunit SA-2, anticorps STAG2, anticorps Stag2, anticorps LOC100175748, anticorps LOC100301585, anticorps LOC100565959, anticorps stag2

Sujet: SA2 is a component of the cohesin complex, which is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which, sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. The subunit interacts directly with RAD21 in cohesin complex. Cohesin complexes are composed of a heterodimer between a SMC1 protein (SMC1L1 or SMC1L2) and SMC3, which are attached via their hinge domain, and RAD21 links them at their heads, and one STAG protein (STAG1, STAG2 or STAG3). In cohesin complexes, STAG2 is mutually exclusive with STAG1 and STAG3.Synonyms: Cohesin subunit SA-2, SA2, SCC3 homolog 2

ID gène: 10735

NCBI Accession: NP_001036214

UniProt: Q8N3U4

Pathways: Stem Cell Maintenance