Neuroligin 2 anticorps (Internal Region)

N° du produit ABIN374806

Détail du produit anti-Neuroligin 2 anticorps

Antigène: Neuroligin 2 (NLGN2)

Épitope: Internal Region

Reactivité: Humain, Rat, Souris, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Neuroligin 2 est non-conjugé

Application: Western Blotting (WB)

Séquence: C-NPPDTDIRDP GKK

Specificité: This antibody detects Neuroligin-2.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Canine (Dog).
Species reactivity (tested):Human, Rat.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide from the internal region of the protein sequence according to NP_065846.1 Genename: NLGN2

Information d'application

Indications d'application: Peptide ELISA: antibody detection limit dilution 1: 8000. Western blot: Approx 90 kDa band observed in Human Pancreas lysates (calculated MW of90.0 kDa according to NP_065846.1). Recommended concentration: 1-3 μg/mL. An additional band of unknown identity was also consistently observed at 50 kDa. Thisband was successfully blocked by incubation with the immunising peptide. We wouldappreciate any feedback from people in the field - have any such results been reportedwith other antibodies/lysates? Have any further splice variants/modified forms beenreported?
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % Sodium Azide, pH 7.3 with 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Neuroligin 2

Antigène: Neuroligin 2 (NLGN2)

Autre désignation: Neuroligin-2 (NLGN2 Produits)

Synonymes: anticorps Nlgn2, anticorps GB10066, anticorps NLGN2, anticorps CCE-L2, anticorps NV50031, anticorps Nv123771, anticorps NL2, anticorps RP23-422L16.24, anticorps neuroligin 2, anticorps LOC410779, anticorps NLGN2, anticorps LOC663865, anticorps LOC100123771, anticorps Nlgn2

Sujet: Neuroligins are cell adhesion proteins that are thought to instruct the formation and alignment of synaptic specializations. The three known rodent neuroligin isoforms share homologous extracellular acetylcholinesterase-like domains that bridge the synaptic cleft and bind beta-neurexins. All neuroligins have identical intracellular C-terminal motifs that bind to PDZ domains of various target proteins. Neuroligin 2 is exclusively localized to inhibitory synapses in rat brain and dissociated neurons. In immature neurons, neuroligin 2 is found at synapses and also at GABAA receptor aggregates that are not facing presynaptic termini.Synonyms: KIAA1366, NLGN2

ID gène: 57555, 9606

UniProt: Q8NFZ4

Pathways: Cell-Cell Junction Organization, Synaptic Membrane