Aromatase anticorps (Internal Region)

N° du produit ABIN374919

Détail du produit anti-Aromatase anticorps

Antigène: Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))

Épitope: Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Aromatase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Séquence: C-HDLSLHPDET KN

Specificité: This antibody is expected to recognise both reported isoforms (NP_000094.2 and NP_112503.1), which are identical

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogène: Peptide with sequence from the internal region of Human CYP19A1.

Information d'application

Indications d'application: ELISA: 1/128000. Western blot: 0.1-0.3 μg/mL. Detects a band of approx. 50-55 kDa in Human Placenta lysates. Immunohistochemistry on Paraffin Sections: 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Aromatase

Antigène: Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))

Autre désignation: Aromatase (CYP19A1 Produits)

Synonymes: anticorps ARO, anticorps ARO1, anticorps CPV1, anticorps CYAR, anticorps CYP19, anticorps CYPXIX, anticorps P-450AROM, anticorps Aromatase, anticorps Cyp19, anticorps Cyp19a, anticorps p450arom, anticorps P450 arom, anticorps aro, anticorps cyp19, anticorps cyp19a, anticorps p450arom-A, anticorps P450AROM, anticorps Ar, anticorps ArKO, anticorps Int-5, anticorps Int5, anticorps CYP19P1, anticorps CYP19A1, anticorps CYP19a1, anticorps P450aromA, anticorps ar1, anticorps cypXIX, anticorps etID309862.18, anticorps zgc:136541, anticorps AroB, anticorps CYP19a2, anticorps P450aromB, anticorps cyp19b, anticorps zgc:92614, anticorps cyp19a1, anticorps cytochrome P450 family 19 subfamily A member 1, anticorps cytochrome P450, family 19, subfamily a, polypeptide 1, anticorps cytochrome P450 family 19 subfamily A member 1 L homeolog, anticorps aromatase, anticorps cytochrome P450 aromatase, anticorps cytochrome P450, family 19, subfamily A, polypeptide 1, anticorps cytochrome P450 19A1, anticorps cytochrome P450, family 17, subfamily A, polypeptide 1, anticorps cytochrome P450, family 19, anticorps cytochrome P450, family 19, subfamily A, polypeptide 1a, anticorps cytochrome P450, family 19, subfamily A, polypeptide 1b, anticorps cytochrome P450 19A1-like, anticorps CYP19A1, anticorps Cyp19a1, anticorps cyp19a1.L, anticorps SAV_2383, anticorps pfcyp19b-tstr, anticorps CYP19, anticorps cyp19a1a, anticorps cyp19a1b, anticorps LOC101174651

Sujet: Aromatase is a key enzyme in steroidogenesis and plays an important role in sexual differentiation, oestrogen biosynthesis, fertility and carcinogenesis. It is highly conserved amongst mammals, and is highly expressed in placental tissue. Many environmental chemicals may influence aromatase activity and thereby disrupt endocrine function.Synonyms: ARO1, CYAR, CYP19, CYP19A1, CYPXIX, Cytochrome P450 19A1, Estrogen synthetase, P450AROM

Poids moléculaire: 57.9kDa (NP_000094.2 and NP_112503.1).

ID gène: 1588, 9606

UniProt: P11511

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis