C14orf169 + NO66 anticorps (Internal Region)

N° du produit ABIN374928

Détail du produit anti-C14orf169 + NO66 anticorps

Antigène: C14orf169 + NO66 (C14orf169) (Chromosome 14 Open Reading Frame 169 (C14orf169))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp C14orf169 + NO66 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to C14orf169 / NO66.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-GAQHSDSKDPR, from the internal region of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/64000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur C14orf169 + NO66

Antigène: C14orf169 + NO66 (C14orf169) (Chromosome 14 Open Reading Frame 169 (C14orf169))

Autre désignation: NO66 (C14orf169 Produits)

Synonymes: anticorps LOC453015, anticorps C10H14orf169, anticorps MAPJD, anticorps NO66, anticorps ROX, anticorps C14orf169, anticorps No66, anticorps im:7141580, anticorps no66, anticorps chromosome 14 open reading frame 169, anticorps ribosomal oxygenase 1, anticorps chromosome 5 open reading frame, human C14orf169, anticorps LOC453015, anticorps Bm1_08415, anticorps RIOX1, anticorps C5H14ORF169, anticorps Riox1, anticorps riox1

Sujet: C14orf169 is the human homolog of Xenopus xNO66. xNO66 is a highly conserved dual location protein in the nucleolus and in a special type of synchronously replicating chromatin. It is a novel, ubiquitous protein, which in most cell types appears to be a constitutive nucleolar component. Immunolocalization studies have revealed that this protein is highly conserved during evolution and shows in most cells analyzed a dual localization pattern, i.e., a strong enrichment in the granular part of nucleoli and in distinct nucleoplasmic entities. Colocalizations with proteins Ki-7, HP1alpha, and PCNA, respectively, have further shown that the staining pattern of xNO66 overlaps with certain clusters of late replicating chromatin. Biochemical experiments have revealed that protein NO66 cofractionates with large preribosomal particles but is absent from cytoplasmic ribosomes. It is proposed that in addition to its role in ribosome biogenesis protein xNO66 has functions in the replication or remodeling of certain heterochromatic regions.Synonyms: C14orf169, Nucleolar protein 66, hsNO66

ID gène: 79697

NCBI Accession: NP_078920

UniProt: Q9H6W3