DHX58 anticorps (C-Term)

N° du produit ABIN374958

Détail du produit anti-DHX58 anticorps

Antigène: DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

Épitope: C-Term

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp DHX58 est non-conjugé

Application: Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to LGP2.

Purification: Affinity chromatography

Immunogène: Peptide with sequence DFLQHCAENLSD, from the C Terminus of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/8000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DHX58

Antigène: DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

Autre désignation: DHX58 (DHX58 Produits)

Synonymes: anticorps MGC82787, anticorps DHX58, anticorps lgp2, anticorps D11LGP2, anticorps D11lgp2e, anticorps LGP2, anticorps RLR-3, anticorps B430001I08Rik, anticorps D11Lgp2e, anticorps LPG2, anticorps Lgp2, anticorps RGD1310093, anticorps DEXH-box helicase 58 L homeolog, anticorps DExH-box helicase 58, anticorps probable ATP-dependent RNA helicase DHX58, anticorps DEXH (Asp-Glu-X-His) box polypeptide 58, anticorps DEXH-box helicase 58, anticorps dhx58.L, anticorps DHX58, anticorps dhx58, anticorps LOC100566102, anticorps Dhx58

Sujet: Anti viral innate immune responses are triggered by pathogen associated molecular patterns (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms. The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids. Other proteins that play similar roles, such as RIG-1 and MDA5 are members of a CARD-helicase family and are expressed in the cytoplasm. A third protein, DHX58, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain. It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling. At least four isoforms of DHX58 are known to exist.Synonyms: ATP-dependent RNA helicase DHX58, ATP-dependent helicase LGP2, D11LGP2E, DHX58, LGP2, Protein D11Lgp2 homolog

ID gène: 79132

NCBI Accession: NP_077024

UniProt: Q96C10