CACNB4 anticorps (C-Term, Internal Region)

N° du produit ABIN375181

Détail du produit anti-CACNB4 anticorps

Antigène: CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))

Épitope: C-Term, Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp CACNB4 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to CACNB4.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-DYPDSYQDTYKPH, from the internal region (near the C Terminus) of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/4000. Western Blot: 0.2 - 0.6 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CACNB4

Antigène: CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))

Autre désignation: CACNB4 (CACNB4 Produits)

Synonymes: anticorps CAB4, anticorps CACNLB4, anticorps EA5, anticorps EIG9, anticorps EJM, anticorps EJM4, anticorps EJM6, anticorps 3110038O15Rik, anticorps Cchb4, anticorps lethargic, anticorps lh, anticorps CACNB4, anticorps cacnb4.2, anticorps calcium voltage-gated channel auxiliary subunit beta 4, anticorps calcium channel, voltage-dependent, beta 4 subunit, anticorps calcium channel, voltage-dependent, beta 4a subunit, anticorps CACNB4, anticorps Cacnb4, anticorps cacnb4.1, anticorps cacnb4, anticorps cacnb4a

Sujet: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. CACNB4 is expressed predominantly in the cerebellum and kidney. Defects in CACNB4 are a cause of idiopathic generalized epilepsy (IGE). IGE is characterized by recurrent generalized seizures. Defects in CACNB4 are also a cause of juvenile myoclonic epilepsy (JME). JME is a common epileptic syndrome characterized by afebrile seizures, onset in adolescence (rather than in childhood) and myoclonic jerks.Synonyms: CAB4, CACNLB4, Calcium channel voltage-dependent subunit beta 4, Voltage-dependent L-type calcium channel subunit beta-4

ID gène: 785

NCBI Accession: NP_000717

UniProt: O00305

Pathways: cAMP Metabolic Process, Skeletal Muscle Fiber Development