DACH1 anticorps (Internal Region)

N° du produit ABIN375187

Détail du produit anti-DACH1 anticorps

Antigène: DACH1 (Dachshund 1 (DACH1))

Épitope: Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp DACH1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to Dachshund homolog 1. This antibody is expected to recognise all three reported isoforms.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Dog, Pig.
Species reactivity (tested):Human.

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography

Immunogène: Peptide with sequence SPVENTPQNNECK, from the internal region of the protein sequence

Information d'application

Indications d'application: ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur DACH1

Antigène: DACH1 (Dachshund 1 (DACH1))

Autre désignation: DACH1 (DACH1 Produits)

Synonymes: anticorps DACH, anticorps AI182278, anticorps Dac, anticorps Dach, anticorps E130112M23Rik, anticorps dach, anticorps dachshund family transcription factor 1, anticorps dachshund 1 (Drosophila), anticorps dachshund family transcription factor 1 S homeolog, anticorps dachshund homolog 1, anticorps DACH1, anticorps Dach1, anticorps dach1.S, anticorps dach1, anticorps LOC100550020

Sujet: DACH1 is similar to the Drosophila melanogaster dachshund gene, which encodes a nuclear factor essential for determining cell fates in the eye, leg, and nervous system of the fly. It is a member of the Ski gene family and is thought to be involved in eye development. Four alternatively spliced transcripts encoding different isoforms have been described for this gene. (from Entrez gene). DACH1 has also been found to inhibit oncogene-mediated breast tumor growth via downregulation of cyclin D1. Expression of DACH1 has been found to inversely correlate with metastasis.Synonyms: (Drosophila), DACH, DACH-1, Dachshund homolog 1, FLJ10138, OTTHUMP00000040839, RP11-512J14.1

ID gène: 1602

NCBI Accession: NP_004383

UniProt: Q9UI36

Pathways: Feeding Behaviour