GRIK1 anticorps (C-Term, Internal Region)

N° du produit ABIN375203

Détail du produit anti-GRIK1 anticorps

Antigène: GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))

Épitope: C-Term, Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIK1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to GLuR5. This antibody is expected to recognise both reported isoforms.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography

Immunogène: Peptide with sequence QCKQTHPTNSTS, from the internal region (near the C Terminus) of the protein sequence

Information d'application

Indications d'application: ELISA: 1/8000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GRIK1

Antigène: GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))

Autre désignation: Glutamate Receptor 5 / GLUR5 (GRIK1 Produits)

Synonymes: anticorps GRIK1, anticorps grik1, anticorps fv36b03, anticorps wu:fv36b03, anticorps EAA3, anticorps EEA3, anticorps GLR5, anticorps GLUR5, anticorps GluK1, anticorps A830007B11Rik, anticorps D16Ium24, anticorps D16Ium24e, anticorps GluK5, anticorps Glur-5, anticorps Glur5, anticorps Glurbeta1, anticorps GluR5, anticorps glutamate ionotropic receptor kainate type subunit 1, anticorps glutamate receptor, ionotropic, kainate 1a, anticorps glutamate receptor, ionotropic, kainate 1, anticorps GRIK1, anticorps grik1a, anticorps Grik1

Sujet: Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors (mGluRs). Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR1 7, NMDA1 3, KAI 2) which comprise ligand gated calcium channels. Metabotropic glutamate receptors are G protein coupled receptors that contain 7 membrane spanning domains and a large extracellular N terminal region. When activated, they can activate phopholipases or adenylylcyclase, depending on the neuron. The group I receptors mGluR1 and mGluR5 activate phospholipase C. By screening a human brain cDNA library with a rat mGluR1 alpha cDNA under low stringency conditions, Minakami et al. (1993) and Minakami et al. (1994) isolated human cDNAs encoding mGluR5. Minakami et al. (1993) identified a longer isoform of mGluR5 (mGluR5B).Synonyms: EAA3, Excitatory amino acid receptor 3, GRIK1, Glutamate receptor ionotropic kainate 1

ID gène: 2897

NCBI Accession: NP_000821

UniProt: P39086

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity