MTHFD1 anticorps (AA 535-562)

N° du produit ABIN389285

Détail du produit anti-MTHFD1 anticorps

Antigène: MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))

Épitope: AA 535-562

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTHFD1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This MTHFD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 535-562 amino acids from the Central region of human MTHFD1.

Clone: RB19391

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur MTHFD1

Antigène: MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))

Autre désignation: MTHFD1 (MTHFD1 Produits)

Synonymes: anticorps MTHFC, anticorps MTHFD, anticorps Tb07.27M11.970, anticorps Dcs, anticorps E430024A07Rik, anticorps Mthfd, anticorps GB13160, anticorps cb325, anticorps fc29f07, anticorps mthfd1, anticorps wu:fc29f07, anticorps zgc:55597, anticorps methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1, anticorps C-1-tetrahydrofolate synthase, cytoplasmic, anticorps putative C-1-tetrahydrofolate synthase, cytoplasmic, anticorps putative C-1-tetrahydrofolate synthase,cytoplasmic, anticorps methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like, anticorps methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase, anticorps methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b, anticorps c-1-tetrahydrofolate synthase, cytoplasmic, anticorps methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase L homeolog, anticorps methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase, anticorps MTHFD1, anticorps Mthfd1, anticorps Tc00.1047053509509.20, anticorps Tc00.1047053511741.50, anticorps Tc00.1047053511517.60, anticorps Tc00.1047053508207.240, anticorps Tb927.7.1600, anticorps LINJ_26_0310, anticorps LBRM_26_0350, anticorps LMJF_26_0320, anticorps mthfd1l, anticorps LOC550749, anticorps mthfd1b, anticorps Tsp_00651, anticorps mthfd1.L, anticorps mthfd1, anticorps LOC589933, anticorps LOC100634307

Sujet: MTHFD1 is a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.

Poids moléculaire: 101559

ID gène: 4522

NCBI Accession: NP_005947

UniProt: P11586

Pathways: Methionine Biosynthetic Process