CREB1 anticorps (pSer133)

N° du produit ABIN389547

Cité dans 1 publication. Cet anticorps anti-CREB1 Polyclonal Lapin (Clone RB05198) (ABIN389547) détecte spécifiquement CREB1 dans WB, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CREB1 anticorps (pSer133) (ABIN389547)

Antigène: CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CREB1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB05198

Détail du produit anti-CREB1 anticorps

Épitope: pSer133

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CREB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S133 of human CREB.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:500. WB: 1:500. WB: 1:500. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-CREB1 (ABIN389547)

Abe, Matsui, Watanabe: "Transgenic songbirds with suppressed or enhanced activity of CREB transcription factor." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 24, pp. 7599-604, (2015) (PubMed).

Détails sur CREB1

Antigène: CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))

Autre désignation: CREB

Sujet: CREB is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, (CRE), a sequence present in many viral and cellular promoters. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway.

Poids moléculaire: 35136

ID gène: 1385

NCBI Accession: NP_004370, NP_604391

UniProt: P16220

Pathways: Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation