BRAF anticorps (pThr598)
Aperçu rapide pour BRAF anticorps (pThr598) (ABIN389791)
Antigène
Voir toutes BRAF AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- pThr598
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Homologie
- C, M, B, Rat
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This BRAF Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T598 of human BRAF.
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Isotype
- Ig Fraction
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Indications d'application
- DB: 1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
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Autre désignation
- BRAF
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Sujet
- BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neuron. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.
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Poids moléculaire
- 84437
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ID gène
- 673
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NCBI Accession
- NP_004324
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UniProt
- P15056
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Pathways
- Signalisation MAPK, Signalisation RTK, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy
Antigène
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