PIK3 gamma anticorps (C-Term)
Aperçu rapide pour PIK3 gamma anticorps (C-Term) (ABIN392567)
Antigène
Voir toutes PIK3 gamma (PIK3CG) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 1074-1102, C-Term
-
Homologie
- M, Pig
-
Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
-
Immunogène
- This PI3KCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1074-1102 amino acids from the C-terminal region of human PI3KCG.
-
Isotype
- Ig Fraction
-
-
-
-
Indications d'application
- WB: 1:1000. IHC-P: 1:50~100
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
Date de péremption
- 6 months
-
-
- PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))
-
Autre désignation
- PI3KCG
-
Sujet
- PI3KCG belongs to the pi3/pi4-kinase family of proteins. This protein is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells.
-
Poids moléculaire
- 126454
-
ID gène
- 5294
-
NCBI Accession
- NP_001269355, NP_001269356, NP_002640
-
UniProt
- P48736
-
Pathways
- Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Signalisation TLR, Inositol Metabolic Process, Hepatitis C, VEGF Signaling
Antigène
-