PIK3 gamma anticorps (AA 1-100)
Aperçu rapide pour PIK3 gamma anticorps (AA 1-100) (ABIN5542535)
Antigène
Voir toutes PIK3 gamma (PIK3CG) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-100
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Fonction
- PIK3CG Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human PIK3CG (AA: 1-100) expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
- ELISA: 1/10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))
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Autre désignation
- PIK3CG
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Sujet
- This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.
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Poids moléculaire
- 126.5 kDa
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ID gène
- 5294
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UniProt
- P48736
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Pathways
- Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Signalisation TLR, Inositol Metabolic Process, Hepatitis C, VEGF Signaling
Antigène
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