TRPM7 anticorps (C-Term)

N° du produit ABIN392614

Détail du produit anti-TRPM7 anticorps

Antigène: TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))

Épitope: AA 1821-1850, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRPM7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This TRPM7 (CHAK1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1821-1850 amino acids from the C-terminal region of human TRPM7 (CHAK1).

Clone: RB3469-3470

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-TRPM7 (ABIN392614)

Inoue, Branigan, Xiong: "Zinc-induced neurotoxicity mediated by transient receptor potential melastatin 7 channels." dans: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7430-9, (2010) (PubMed).

Gavenis, Schumacher, Schneider, Eisfeld, Mollenhauer, Schmidt-Rohlfing: "Expression of ion channels of the TRP family in articular chondrocytes from osteoarthritic patients: changes between native and in vitro propagated chondrocytes." dans: Molecular and cellular biochemistry, Vol. 321, Issue 1-2, pp. 135-43, (2009) (PubMed).

Détails sur TRPM7

Antigène: TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))

Autre désignation: TRPM7 (CHAK1) (TRPM7 Produits)

Synonymes: anticorps cb495, anticorps TRPM7, anticorps chak, anticorps chak1, anticorps ltrpc7, anticorps trp-plik, anticorps ALSPDC, anticorps CHAK, anticorps CHAK1, anticorps LTRPC7, anticorps TRP-PLIK, anticorps 2310022G15Rik, anticorps 4833414K03Rik, anticorps 5033407O22Rik, anticorps LTrpC-7, anticorps Ltpr7, anticorps Ltrpc7, anticorps TRPPLIK, anticorps Chak, anticorps Trp-plik, anticorps transient receptor potential cation channel subfamily M member 7, anticorps transient receptor potential cation channel, subfamily M, member 7, anticorps TRPM7, anticorps trpm7, anticorps Trpm7

Sujet: TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.[supplied by OMIM]

Poids moléculaire: 212697

ID gène: 54822

NCBI Accession: NP_060142

UniProt: Q96QT4