FOXO1 anticorps (AA 242-655)

N° du produit ABIN400650

Cet anticorps anti-FOXO1 Monoclonal Souris (Clone 7h3) (ABIN400650) détecte spécifiquement FOXO1 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour FOXO1 anticorps (AA 242-655) (ABIN400650)

Antigène: FOXO1 (Forkhead Box O1 (FOXO1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FOXO1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 7h3

Détail du produit anti-FOXO1 anticorps

Épitope: AA 242-655

Specificité: This antibody recognizes Human FKHR.

Réactivité croisée (Details): Species reactivity (tested):Human.

Attributs du produit: Synonyms: Forkhead Box Protein O1, FOXO1, FKHR, Forkhead Box Protein O1A, Forkhead inRhabdomyosarcoma

Purification: Protein G Chromatography.

Immunogène: Fusion protein containing the region encoding aa 242-655 of Human FOXO1A expressed inE. coli.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 0.1-2.0 μg/mL. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing no preservatives.

Agent conservateur: Without preservative

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur FOXO1

Antigène: FOXO1 (Forkhead Box O1 (FOXO1))

Autre désignation: FOXO1A

Sujet: FOXO1A (FKHR or ForkHead in Rhabdomyosarcoma) is a 70 kDa protein which is a member of a subfamily of the forkhead homeotic gene family of transcription factors. Recent studies have shown that this protein can act as either a coactivator or a corepressor of nuclear receptor activity. This action is mediated through the LXXLL motif found in the C terminus of the FOXO1A protein. The specific function of the gene has not yet been determined, however, it may play a role in myogenic growth and differentiation. Chromosomal aberrations involving FOXO1A are a cause of rhabdomyosarcoma 2 (RMS2), also known as alveolar rhabdomyosarcoma.Synonyms: FKHR, FOXO1, Forkhead Box Protein O1, Forkhead Box Protein O1A, Forkhead in Rhabdomyosarcoma

ID gène: 2308

UniProt: Q12778

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling