COL18A1 anticorps (Chain alpha 1)

N° du produit ABIN400737

Détail du produit anti-COL18A1 anticorps

Antigène: COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))

Épitope: Chain alpha 1

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp COL18A1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Recognizes Mouse Endostatin (Mr 22 kDa), an unidentified protein is also weakly detected (Mr 52 kDa).

Réactivité croisée (Details): Species reactivity (expected):Human and Rat.
Species reactivity (tested):Mouse.

Attributs du produit: Synonyms: COL18A1, Endostatin, KNO1

Purification: Thiophilic Adsorption Chromatography.

Immunogène: Full-length Recombinant Murine Endostatin.

Clone: 1873-46

Isotype: IgG

Information d'application

Indications d'application: Western blot (Immunoblot). Immunohistochemistry on Paraffin Sections: 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 50 mM Sodium Phosphate, pH 8.0 containing 0.05 % Sodium Azide, before the addition of Glycerol to 30 %.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur COL18A1

Antigène: COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))

Abstract: COL18A1 Produits

Synonymes: anticorps KNO, anticorps KNO1, anticorps KS, anticorps cb371, anticorps cb529, anticorps fc96d06, anticorps sb:cb529, anticorps wu:fb47h10, anticorps wu:fb77g12, anticorps wu:fc50f04, anticorps wu:fc96d06, anticorps wu:fk02h12, anticorps kno, anticorps kno1, anticorps collagen type XVIII alpha 1 chain, anticorps collagen type XVIII alpha 1 chain a, anticorps collagen, type XVIII, alpha 1, anticorps collagen type XVIII alpha 1, anticorps COL18A1, anticorps col18a1a, anticorps Col18a1, anticorps col18a1

Sujet: Endostatin (20-22 kDa), a cleaved product of the C-terminal domain of collagen XVIII, is an endogenous angiogenesis inhibitor. It was originally found in conditioned media from a murine endothelial tumor cell line, hemangioendothelioma. Endostatin inhibits endothelial cell migration (in vivo and in vitro) and induces endothelial cell apoptosis. It inhibits tumor growth and impairs blood vessel maturation in wound healing. Endostatin has an important role in endothelial cell adhesion and cytoskeletal organization. Endostatin can be found in vessel walls (elastic fibers) and basement membranes.Synonyms: COL18A1, Endostatin, KNO1

ID gène: 80781

UniProt: P39060