POGZ anticorps (N-Term)

N° du produit ABIN401435

L’anticorps anti-POGZ Polyclonal Lapin est utilisé pour la détection de POGZ dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Poulet, Macaque, Babouin olive et Chimpanzé. Il a été validé pour WB et EIA.

Aperçu rapide pour POGZ anticorps (N-Term) (ABIN401435)

Antigène: POGZ (Pogo Transposable Element with ZNF Domain (POGZ))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Poulet, Macaque, Babouin olive, Chimpanzé

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POGZ est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-POGZ anticorps

Épitope: N-Term

Specificité: This antibody is known to react with Pogz protein.

Réactivité croisée (Details): Species reactivity (expected):Human, Canine, Cattle, Rat, Chimpanzee, Macaque, Olive Baboon, Chicken, Short-tailed opossum.
Species reactivity (tested):Mouse.

Purification: Affinity chromatography

Immunogène: Synthetic peptide corresponding to a region near the N-terminus of mouse Pogz protein

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/150,000. Western Blot: 1/3,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.564 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur POGZ

Antigène: POGZ (Pogo Transposable Element with ZNF Domain (POGZ))

Autre désignation: POGZ

Sujet: Pogz is a zinc-finger protein containing at least 8 C2H2 zinc fingers, a CENP-B (centromere protein-B) domain, and a DDE domain found in the bacterial transposase/retroviral integrase family. Members of this family of integrases share structural homologies and show similar catalytic activity to the RAG1 and RAG2 proteins that initiate V(D)J recombination in lymphoid progenitors. Mouse Pogz has a human homolog with a base pair similarity of 90 % and amino acid similarity of 93 % for the full length protein. In humans at least 3 variants have been predicted and they are all similar at the N-terminus. A number of expressed sequence tags (ESTAs) cloned from murine undifferentiated ES cells and Lin-/c-Kit+/Sca-1+ hematopoietic stem cell cDNA libraries correspond to the Pogz gene, further underlining an important function for this gene in stem cells. In mice, deletion of the gene in all tissues early in embryogenesis has been shown to be lethal.Synonyms: KIAA0461, Pogo transposable element with ZNF domain, SUHW5, Suppressor of hairy wing homolog 5, ZNF280E, ZNF635

ID gène: 229584

NCBI Accession: NP_766271

UniProt: Q8BZH4